高血压患者室间隔厚度、颈动脉内-中膜厚度及同型半胱氨酸的关系

Thecorelation of ventricular septal thickness,carotid intima-media thickness and homocysteine in hypertension

目的:应用彩色多普勒超声分析不同室间隔厚度的高血压患者颈动脉内-中膜厚度(IMT)及测血浆同型半胱氨酸的变化。方法:选择高血压患者45例,心脏超声检测非室间隔肥厚组20例,室间隔肥厚组25例,应用超声诊断仪检测颈动脉IMT及测血浆HCY浓度。结果:室间隔肥厚组较非室间隔肥厚组IMT明显增厚。室间隔厚度与IMT呈正相关,血浆HCY浓度与血压值成正相关,与室间隔肥厚无明显相关性。结论 :高血压室间隔增厚患者颈动脉损害程度更甚,心脏和血管的超声检查可提示高血压的损害程度。同型半胱氨酸增高可能是高血压形成原因之一。

Objective：Investigate the corelation of carotid artery-medial thickness（IMT）,ventricular septal thickness and the plasma homocysteine（HCY） of hypertensive patients by color Doppler ultrasonography.Methods： 45 hypertensive patients,including 20 non-septal hypertrophy cases and 25 septal hypertrophy cases detected by cardiac ultrasound,ultrasonic diagnostic apparatus detecded the carotid artery IMT and plasma HCY concentration.Results： IMT was significantly thicker in septal hypertrophy group than in the non-septal hypertrophy group.The carotid artery IMT was positively related to ventricular septal thickness.The plasma HCY concentration was positively correlated with blood pressure,but no significant correlation with ventricular septal hypertrophy.Conclusion： The damage of carotid artery was more severe in hypertensive ventricular septal hypertrophy patients.Cadiac and vascular ultrasound could prompt each other for the extent of damage in hypertension.Increased homocysteine may be one of the reasons for hypertension.