期刊文献+

国产与进口阿托伐他汀治疗高脂血症的临床疗效Meta分析 被引量:2

下载PDF
导出
摘要 高脂血症是临床上常见的一种的心血管症状,主要表现为脂质代谢紊乱,可表现为一种或几种脂类化合物代谢异常,是造成各种心脑血管疾病的重要危险因素。阿托伐他汀为HMG-CoA还原酶选择性抑制剂,其调脂作用明显,主要用于降低血浆胆固醇(TC)和低密度脂蛋白(LDL-C)。近年来,陆续有文献对国产与进口的阿托伐他汀的降脂作用进行比较,但仍缺乏有力的循证学证据。笔者查阅了近年来发表的文献,并进行Meta分析,报告如下。
作者 李锦绣
出处 《河北医药》 CAS 2012年第23期3613-3614,共2页 Hebei Medical Journal
  • 相关文献

参考文献4

二级参考文献15

  • 1陈小容,聂本刚.阿托伐他汀钙对血管性认知障碍合并高脂血症患者的血脂及认知功能的影响[J].中国全科医学,2009,12(15):1382-1384. 被引量:31
  • 2叶任高,陆再英,主编.内科学[M].第6版.北京:人民卫生出版社,2005,28-30.
  • 3Nawrocvki JW, Weiss SR, Davidson MH, et al. Reduction of LDL cholesterol by 25% to 60% in patients with primary_ hypercholesterolemia by atorvastatin, a new HMG-A reductase inhibitor [ J ]. Arterioscler Thromb Vasc Biol, 1995,15 (2) :678-682.
  • 4Rebecca G, BakkerA, Davidson MH, et al, Efficacy and safety of a new HMG-CoA reductase inhibitor: atorvastatin,in patients with hypertriglyceridemia [ J ]. JAMA, 1996,275 (2) : 128-133.
  • 5Pederson JR,Olsson AG,Faergemen V,et al.Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian simvastatin sarvival studu(4s)[J].lirculafion,1998,97:1453-1460.
  • 6Flaker GC,Wamica JW,Sacks FM,et al.For the cholesterol and Recueht Event(CARE)investigators.Pravastain prevents clinical events in revascularized patients with average cholesterol concentrations[J].J Am Coll Cardiol,1999,34:106-112.
  • 7Krone W,Muller WD.Lipid-lowering therapy and stabieization of aherosclerotic plagues[J].Thromb Haecmost,1999,82 csuppl 17:60-65.
  • 8Dupuis J,Tardif JC,Cernack P,et al.cholesterol redaction rapidly improves endothelial fanction after acute coronary syndromes:the RECIFE trial[J].Circulation,1999,99:3227-3333.
  • 9方圻,王钟林,宁田海,邵耕,陈在嘉,陆宗良,李健斋,林传骧,周北凡,诸骏仁,诸永康,陶萍,陶寿淇,龚兰生,顾复生,游凯,戴玉华.血脂异常防治建议[J].中华心血管病杂志,1997,25(3):169-175. 被引量:3067
  • 10张蕾,蔡运昌.他汀类降脂药的临床应用研究进展[J].贵州医药,2009,33(2):176-179. 被引量:15

共引文献24

同被引文献34

  • 1李继远.国产阿托伐他汀治疗原发性高脂血症的疗效和安全性的随机临床对照研究[J].医学信息(西安上半月),2005,18(10):1382-1383. 被引量:6
  • 2王红卫,喻卓,付先平.国产阿托伐他汀治疗冠心病并发高脂血症疗效观察[J].云南医药,2007,28(3):241-243. 被引量:7
  • 3郑欣,韩洁.国产和进口阿托伐他汀降脂作用临床观察[J].河南大学学报(医学版),2007,26(3):53-54. 被引量:5
  • 4国家食品药品监督管理局.药品注册管理办法[S].2007.
  • 5WHO. TRS937-2006,Annex 4 Supplementary guidelineson good manufacturing practice[S].2015.
  • 6Kesselheim AS,Misono AS,Lee JL,et al. Clinical equivalenceof generic and brand-name drugs used in cardiovasculardisease:a systematic review and meta-analysis[J]. JAMA,2008,300(21):2 514.
  • 7Boh M,Opolski G,Poredos P,et al. Therapeutic equivalenceof the generic and the reference atorvastatin in patientswith increased coronary risk[J]. Int Angiol. 2011,30(4):366.
  • 8Kim S,Park K,Hong S,et al. Efficacy and tolerabilityof a generic and a branded formulation of atorvastatin 20mg/d in hypercholesterolemic Korean adults at high riskfor cardiovascular disease:a multicenter,prospective,randomized,double-blind,double-dummy clinical trial[J]. Clinical Therapeutics,2010,32(11):1 896.
  • 9Kim S,Seo M,Yoon M,et al. Assessment of the Efficacyand tolerability of 2 formulations of atorvastatin in Koreanadults with hypercholesterolemia:a multicen- ter,prospective, open-Label, randomized trial[J]. ClinicalTherapeutics,2013,35(1):77.
  • 10Boonbaichaiyapruck S,Cheepudomwit S,Panjavenin P,et al. Effect of atorvastatin on LDL & hs-CRP in a selectedThai population[J]. J Med Assoc Thai,2008,91(8):1 189.

引证文献2

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部