微量循环肿瘤细胞检测技术的研究进展
摘要
肿瘤的发生发展是一个多基因参与，多因素、多步骤的复杂的生物学过程。肿瘤刚发生时多为器官局限性疾病，绝大多数肿瘤组织通过其脱落细胞进入血液循环，进而侵袭其它脏器进行远处转移。早于1869年，Ashworth在一例肿瘤死亡患者外周血中发现了类似肿瘤细胞，并首次提出循环肿瘤细胞（Circulating Tumor Cells，CTCs）的概念。
出处
《微循环学杂志》
2012年第4期67-70,共4页
Chinese Journal of Microcirculation
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