新生儿血小板减少症相关因素的分析

Analysis of related factors and clinical characteristics of neonatal thrombocytopenia

目的:探讨新生儿血小板减少症(NT)的相关因素、临床特点、预后及与危重评分的关系。方法:将89例新生儿NT患儿根据血小板减少程度分为轻度组和重度组,分析NT相关因素、治疗、预后及与危重评分的关系。结果:重度组血小板恢复至正常时间明显长于轻度组(P<0.05);重度组红细胞计数、危重评分明显低于轻度组(P<0.05～P<0.01),C反应蛋白、败血症患病率明显高于轻度组(P<0.05～P<0.01)。结论:感染是NT的最主要因素,血小板减少程度与危重评分关系密切,早期诊断及时病因治疗至关重要,大多数患儿预后良好。

Objective：To investigate the relationship of the related factors,clinical characteristics,prognosis and severity score of neonatal thrombocytopenia（NT）. Methods：Eighty-nine infants with NT were collected in neonatal intensive care unit,these patients were divided into mild group and severe group.The related factors,treatment,prognosis and relationship with the severity score were analyzed. Results：Compared with mild group,the recovery time of platelet in severe group was prolonged（P0.05）,red blood cell count and severity score were decreased,C reactive protein and incidence of were increased,there were significant differences（P0.05-0.01）. Conclusions：Infection is the key factor of NT,there is very close relationship between the level of platelet and severity score.Early diagnosis and treatment is very crucial,and most patients have a favorable prognosis.