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2型糖尿病的全基因组关联研究进展 被引量：12

Progress in genome-wide association study of type 2 diabetes
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摘要 2型糖尿病是环境和遗传因素共同作用的结果,遗传因素的研究在2006年以前主要是基于连锁分析和候选基因策略,近年来全基因组关联研究的出现使2型糖尿病遗传易感性的研究进入了一个崭新的阶段,发现了很多新的易感基因或区域,为其病因学研究及防治提供新的思路。 Type 2 diabetes is the result of both environmental and genetic factors. Before 2006, the study of genetic factors was based on linkage analysis and candidate gene strategy, but it was very slow and difficult. With the emergence of genome-wide association study, the researches on genetic susceptibility of type 2 diabetes have entered a new phase, and found a lot of new susceptibility genes or regions, thereby provide new ideas for the cause of type 2 diabetes and prevention.
作者 陆凤 钱云 沈洪兵
机构地区 南京医科大学公共卫生学院流行病与卫生统计学系 无锡市疾病预防控制中心健康促进部
出处 《中华疾病控制杂志》 CAS 北大核心 2012年第11期989-994,共6页 Chinese Journal of Disease Control & Prevention
基金 国家自然科学基金(81072379) 无锡市科技项目(CSE01016)
关键词 糖尿病 2型 基因组 研究 疾病遗传易感性 Diabetes mellitus, type 2 Genome Research Genetic predisposition to disease
分类号 R181.3 [医药卫生—流行病学] R587.1 [医药卫生—内分泌]
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参考文献29

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二级参考文献43

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共引文献36

同被引文献189

引证文献12

二级引证文献87

中华疾病控制杂志
2012年 第11期

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