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308 nm准分子激光治疗白癜风疗效与影响因素分析 被引量:2

Efficacy and influencing factors of 308 nm excimer laser in the treatment of vitiligo
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摘要 目的:评价308 nm准分子激光治疗白癜风的疗效及其影响因素。方法:采用308 nm准分子激光系统治疗103例白癜风患者171处皮损,每周治疗1~2次,共12~50次,治疗结束后评价疗效。结果:皮损的总显效率为59.06%,有效率为83.04%。疗效影响因素分析显示不同部位、年龄、病程以及皮损大小对治疗效果有显著影响。结论:308 nm准分子激光治疗白癜风疗效高、副作用少。 Objective: To assess the efficacy and influencing factors of 308 nm excimer laser in the treatment of vitiligo. Methods: One hundred and seventy- one lesions of 103 patients with vitiligo were treated with 308 nm exelmer laser, one to two times per week for 12 - 50 times. Efficaeies were evaluated after the treatment completed. Results: The total efficacy and remarkable efficacy were 59.06% and 83.04%, respectively. The site of the lesion, age, duration of the disease and the lesion size were positively correlated to the therapeutic effects ( P 〈 0.01). Conclusion: 308 nm excimer laser is safe and effective in treating vitiligo.
出处 《中国麻风皮肤病杂志》 2012年第11期767-770,共4页 China Journal of Leprosy and Skin Diseases
基金 江苏省卫生厅科研项目(编号:H201219)
关键词 308NM准分子激光 白癜风 疗效 308 nm excimer laser vitiligo efficacy
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参考文献6

  • 1Park KK, Liao W, Murase JE. A raeview of monochromatic excimerlight (MEL) in vitiligo. Br J Dermatol,2012,6:1365 - 2133.
  • 2白癜风临床分型及疗效标准(2003年修订稿)[J].中华皮肤科杂志,2004,37(7):440-440. 被引量:801
  • 3Grimes PE. New insights and new therapies in vitiligo. JAMA, 2005,293(6) :730 - 735.
  • 4Hofer A, Hassan AS, Legat FJ, et al. The efficacy of excimer laser (308rim) for vitiligo at different body sites. J Eur Acad DermatolVenereol, 2006,20(5) :558 - 564.
  • 5杨晶,谷雪红,李媛丽,王家璧.308nm准分子激光治疗稳定期白癜风疗效观察[J].中国中西医结合皮肤性病学杂志,2009,8(3):158-159. 被引量:7
  • 6Esposito M, Soda R, Costanzo A, et al. Treatment of vitiligo with the 308 nm excimer laser. Clin Exp Dermatol, 2004,29(2) : 133 - 137.

二级参考文献5

  • 1白癜风临床分型及疗效标准(2003年修订稿)[J].中华皮肤科杂志,2004,37(7):440-440. 被引量:801
  • 2Choi KH,Park JH,Ro YS.Treatment of Vitiligo with 308nm xenon-chloride excimer laser:therapeutic efficacy of different initial doses according to treatment areas[J].J Dermatol,2004,31:284-292.
  • 3Kostovic K,Nola I,Bucan Z,et al.Treatment of vitiligo:current methods and new approaches[J].Acta Dermatovenerol Croat,2003,11:163-170.
  • 4Hang SB,Park HH,Lee MH.Short-term effects of 308nm xenonchloride exeimer laser and narrow-band ultraviolet B in the treatment of vitiligo:a comparative study[J].J Korean Medsci,2005,20:273-278.
  • 5Hofer A,Hassan AS,Legat FJ,et al.The efficacy of excimer laer (308 nm) for vitiligo at different body sites[J].J Eur Acad Dermatol Venereol,2006,20:558-564.

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