腹水超滤浓缩回输治疗难治性腹水临床观察

Effect of reinfusion of concentrated ascites fluid on refractory ascites

目的观察腹水超滤浓缩回输治疗难治性腹水临床疗效。方法将43例肝硬化患者随机分为两组,对照组20例,给予卧床休息,限钠、水,输血浆、白蛋白,利尿,护肝和适当放腹水加输白蛋白等综合治疗。治疗组23例,仅给予基础护肝和配合腹水超滤浓缩回输仪,自体腹水浓缩后回输入腹腔。观察患者治疗前后症状、体征、体重、尿量、血浆蛋白、血钠、钾变化和平均住院日及住院费用情况。结果治疗组患者治疗后体重、尿量、白蛋白、血肌酐、血钠钾指标及平均住院日及住院费用优于对照组,差异有统计学意义(P<0.05)。结论腹水超滤浓缩回输治疗肝硬化腹水,疗效好、住院费用少,值得临床推广。

Objective To observe the clinical efficacy of ultrafiltration transfusion treatment of concentrated ascites for refractory ascites.Methods Forty-three patients with liver cirrhosis were randomly divided into two groups,20 cases in control group were given comprehensive treatment such as bed rest,restriction of salt and water,transmission of blood and albumin,diuretic,liver protection,and appropriate paracentesis plus lose albumin.Twenty-three cases in treatment group were given liver protection and reinfusion of concentrated ascites fluid to the abdominal cavity by ascites reinfusion instrument.The symptoms,signs,body weight,urine volume,plasma protein,serum sodium,serum potassium,the average length of hospital stay and hospital costs were observed.Results The body weight,urine output,serum albumin,serum creatinine,serum sodium,serum potassium and the average length of hospital stay and hospitalization costs were suporior than those in the control group,the differences were significant（P0.05）.Conclusion The effect of ultrafiltration transfusion of concentrated ascites on liver cirrhosis is good,and with less hospitalization costs,worthy of promotion.