预防服药对减少荧光素眼底血管造影不良反应的作用

Effect of preventive medicine on reducing adverse reaction of fundus fluorescein angiography

目的:探讨预防服药对减少荧光素眼底血管造影过程中发生不良反应的疗效。方法:将3640例行荧光素钠眼底血管造影检查的患者随机分为观察组和对照组各1820例。对照组在造影检查前只散瞳不服药,观察组则在造影检查前除散瞳外,造影前20 min给予维生素B620mg,马来酸氯苯那敏片4 mg口服,观察造影过程中出现的不良反应情况。结果:观察组中不良反应发生率为2.31%,对照组为6.76%,两组相比差异有统计学意义。结论:荧光素钠眼底血管造影检查前予预防服药可减少不良反应的发生。

Objective：To evalute the effect of preventive medication to reduce untoward effect in fandus fluorescein angiog-raphy（FFA）.Methods：Total 3640 cases with FFA were divided into two groups randomly.The patients in control group（n=1820） were given topical mydriasis without oral medication,while patients in the research group（n=1820）were given vitamin B6 20 mg and chlorpheniramine maleate tablets 4 mg except for giving topical mydriasis.Both groups received follow-up examination with untoward effect.Results：The rates of untoward effect in the research group and control group were 2.31% and 6.78%.There was significant difference with each other in the two groups（P0.05）.Conclusion：Preventive medication before FFA is effective in preventing the untoward effect.