摘要
目的:探讨紫杉醇脂质体联合顺铂治疗晚期食管癌的最佳护理方法,以最大限度的减少毒副作用,提高患者的舒适度和用药安全性。方法:对30例晚期食管癌患者使用紫杉醇脂质体135~175 mg/m2静脉滴注3 h,使用1 d;顺铂30 mg/m2,静脉滴注,使用1~4 d;21 d或28 d为1个周期。用药期间对患者进行心理护理、饮食护理、生活护理、用药护理,观察护理效果。结果:30例患者评价疗效满意,顺利完成治疗。毒性反应较小,主要是骨髓抑制、消化道毒性、神经毒性和脱发。结论:加强用药期间的护理和病情观察,严格执行化疗方案,可有效减少毒副反应,保障化疗的顺利完成。
Objective:To explore the best care of advanced esophageal cancer treated by paclitaxel liposomes in combination with cisplatin,minimize toxic side effects,improve the patient′s comfort and safety of medication.Methods:30 cases of advanced esophageal cancer patients using 135-175 mg/m2 dL intravenous infusion of paclitaxel liposome 3 hours on the first day,30 mg/m2 dL intravenous infusion of cisplatin from the first day to fourth day,21 or 28 days as a cycle.Do psychological care,dietary care,life care,medication care for patients and observe care effects during chemotherapy.Results:30 patients evaluate the efficacy satisfied,successfully completed with chemotherapy.Toxic reaction was mild,mainly include bone marrow suppression,gastrointestinal toxicity,neurotoxicity,and alopecia.Conclusion:Strengthen the care and disease observation during chemotherapy,strictly enforce the the chemotherapy regimen,can effectively reduce the toxicity and protect the chemotherapy successful completion.
出处
《护理实践与研究》
2012年第20期66-67,共2页
Nursing Practice and Research
关键词
紫杉醇脂质体
顺铂
晚期食管癌
化疗
护理
Paclitaxel liposome
Cisplatin
Advanced esophageal cancer
Chemotherapy
Nursing