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脑微出血相关因素分析 被引量：5

Analysis of influence factors of cerebral microbleeds
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摘要 目的对比有无脑微出血2组的临床生化和脑白质疏松患病率,探讨其发病机制。方法 64例神经内科住院患者按照头颅磁共振结果分为脑微出血组22例和对照组42例,分析2组患者纤维蛋白原、总胆固醇、低密度脂蛋白、高密度脂蛋白含量及脑白质疏松患病率。结果脑微出血组患者低密度脂蛋白水平低于对照组,总胆固醇水平明显高于对照组。脑微出血组患者脑白质疏松的患病率高于对照组。结论脑微出血和脑白质疏松具有显著相关性,保持血脂正常对脑微出血患者有重要意义。 Objective To investigate the level of clinical biochemistry and leukoaraiosis in patients with cerebral microbleeds（CMB） to approach the pathogenesis.Methods According to the results of MRI,64 patients were divided into two groups： CMB group（n=22） and control group（n=42）.The levels of fibrinogen,cholesterol,low density lipoprotein,high density lipoprotein and the rate of leukoaraiosis between the two groups were analyzed.Results The level of low density lipoprotein in patients with CMB was lower than control group.But cholesterol level of CMB group was higher than control group.The prevalence of leukoaraiosis in CMB group was higher than control group.Conclusion The correlation between CMB and LA is significant,maintain normal blood to CMB patients has important significance.
作者 史蕙青
机构地区 河南安阳市第六人民医院神经内科
出处 《中国实用神经疾病杂志》 2012年第21期18-19,共2页 Chinese Journal of Practical Nervous Diseases
关键词 脑微出血 脑白质疏松 纤维蛋白原 总胆固醇 低密度脂蛋白 高密度脂蛋白 Cerebral microbleeds Leukoaraiosis Fibrinogen Cholesterol Low density lipoprotein High density lipoprotein
分类号 R743.34 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献8

  • 1Keonnecke HC. Cerebral microbleeds on MRI: prevalence asso- ciation and potential clinical implications[J]. Neurology, 2006, 66(2) 165-171.
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二级参考文献27

  • 1康笑水,曾庆师,李传福,侯金文,丛培新.MRI不同序列诊断高血压性脑微量出血的价值[J].中华老年医学杂志,2007,26(6):449-450. 被引量：3
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共引文献40

同被引文献33

  • 1Song YM,Sung J,Davey Smith G,et al.Body mass index and ischemic and hemorrhagic stroke:a prospective study in Korean men[J]. Stroke,2004, 35 (4):831-836.
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  • 4Anderson KM,Wilson PW,Garrison RJ,et al.Longitudinal and secular trends in lipoprotein cholesterol measurements in a general population sample.The Framingham Off spring Study[J]. Atherosclerosis, 1987, 68(1-2):59-66.
  • 5Thrift A,McNeil J,Donnan G.Reduced frequency of high cholesterol levels among patients with intracerebral haemorrhage[J].J Clin Neurosci,2002,9:376-380.
  • 6刘波,张巧凤,郑俊婷.脑白质疏松症危险因素的Logistic回归分析[J].包头医学院学报,2007,23(5):475-477. 被引量：5
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  • 10Fisher M,French S,Ji P. Cerebral microbleeds in the elderly a pathological analysis[J].{H}STROKE,2010,(12):2782-2785.

引证文献5

二级引证文献24

中国实用神经疾病杂志
2012年 第21期

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