金鸡纳生物碱-9-O-脯氨酸酯衍生物催化的不对称“中断的”Feist-Bénary反应
Cinchona alkaloid-9-O-proline ester derivatives as organocatalysts for asymmetric interrupted Feist-Bénary reaction
摘要
4种金鸡纳生物碱-9-O-脯氨酸酯衍生物用于催化环己二酮与溴乙酰甲酸乙酯的不对称"中断的"Feist-Bénary反应,得到了高的化学产率(>92%)和最高为72%e.e.的立体选择性。
Four cinchona alkaloid-9-O-proline ester deriva- tives were used to catalyze the asymmetric ＂ interrupted ＂ Feist-Benary reaction of ethyl bromopyruvate bromo-ketoesters and 1,3-cyclohexadione. The corresponding hydroxydihydro- furans were obtained in excellent yields （ 〉 92% ） and with up to 72% e. e..
出处
《化学试剂》
CAS
CSCD
北大核心
2012年第11期1013-1016,共4页
Chemical Reagents
基金
吉林省自然科学基金资助项目(201015237)
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共引文献2
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1钟涛,乐长高,谢宗波,曹霞,吕雪霞.碱性离子液体在有机合成中的应用研究进展[J].有机化学,2010,30(7):981-987. 被引量：13
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2金瑛,张天一,昌盛.金鸡纳生物碱-9-O-三甲基硅衍生物催化的不对称“中断”Feist-Bénary反应[J].应用化学,2012,29(9):1006-1010.
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1金瑛,姚志军,刘鹏,姜茹,张生勇.3，6-二氯哒嗪-金鸡纳生物碱衍生物催化不对称“中断的”Feist-Bénary反应的研究[J].有机化学,2008,28(1):94-98. 被引量：3
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2金瑛,张天一,昌盛.金鸡纳生物碱-9-O-三甲基硅衍生物催化的不对称“中断”Feist-Bénary反应[J].应用化学,2012,29(9):1006-1010.
