虚证便秘患者肛管直肠压力测定及益气润肠液对其影响

Effect of Reinforcing Qi and Moistening Intestine Oral Liquid on Anorectal Manometry of Asthenia Type Constipation Patients

目的：探讨虚证便秘患者肛管直肠压力测定及益气润肠液对其的影响。方法：本研究分健康人组（28例）、益气润肠液组（36例）、麻仁丸组（36例）和西沙比利组（35例），并检测了用药组患者治疗前后肛管最大收缩压、直肠肛管收缩反射、直肠肛管抑制反射、排便反射、直肠阈感觉、直肠最大耐受量。结果：虚证便秘患者直肠感觉功能明显减退，肛管括约肌反应性降低（P＜0．01）；益气润肠液治疗后能有效地改善直肠感觉功能，并提高了肛管括约肌反应性（P＜0．05）。结论：益气润肺液对改善虚证便秘患者肛管直肠动力异常有效。

To study the change of anorectal manometry in asthenia type constipation patients and effect of reinforcing Qi and moistening intestine oral liquid (RQMI) on it. Methods: The fotal of 135 cases were divided into healthy group, RQMI treated group, Maren pill (MRP) treated group and prepulsid (PPS) treated group,their anal maximal voluntary squeez pressure, rectoanal contraction reflex, rectoanal inhibitory reflex, defecation reflex, rectal volume sensory threshold and rectal maximal tolerable volume were observed. Results: The rectal sensory function of patients weakened obviously and anal sphincter reactivity reduced as compared with those of healthy person (P < 0.01 ), and both were improved by RQMI treatment (P <0. 05). Conclusion: RQMI is superior to MRP and prepulside in improving anorectal dynamic abnormality in constipation patient of asthenia type.