银杏叶注射液联合脂必泰胶囊治疗老年冠心病

Ginkgo Leaf Injection Combined with Zhibitai Capsule for Treatment of Senile Coronary Heart Disease

目的:探讨银杏叶注射液联合脂必泰胶囊治疗老年冠心病的可行性及临床疗效。方法:选取2009年5月-2012年5月收治的149例60岁以上的冠心病患者,将其随机分为对照组和观察组。对照组74例,采用银杏叶注射液治疗,观察组75例,在此基础上联合脂必泰胶囊治疗。观察并比较两组患者的临床疗效、血脂变化及血液流变学变化情况。结果:观察组的临床效果明显优于对照组(P<0.05或0.01),治疗后观察组的血脂指标的水平变化和血液流变学指标明显低于对照组(P<0.01)。且两组患者间的不良反应比较无显著性差异。结论:银杏叶注射液联合脂必泰胶囊能有效改善老年冠心病患者的血脂及血液流变学,其临床效果显著,且不良反应少,值得在临床广泛推广。

Objective： To discuss the feasibility and clinical efficacy of ginkgo leaf injection combined with Zhibitai capsuleinthe treatment of senile coronary heart disease. Method： One houndred and forty-nine cases aged more than 60 from May. 2009 to May. 2012 in our hospital were divided into control group and observation group. 74 cases in control group were treated with ginkgo leaf injection, while 75 cases in observation group were added Zhibitai capsule on the basis of control group. The clinical efficacy, changes of blood lipid and hemorheology in two groups were observed and compared. Result： The efficacy of observation group was superior to control group （P 〈 0.05 or 0.01 ）. The change of blood lipid and hemorheology in observation group was obviously lower than that in control group after treatment （P 〈 0.01 ）. The adverse reactions of two groups had no obvious difference. Conclusion： The combination of ginkgo leaf injection and Zhibitai capsule can obviously improve blood lipid and hemorheology of senile coronary heart disease. It has obvious effect with less adverse reactions, which is worth of spreading in clinic.