摘要
目的:研究芦笋提取物对氧化应激小鼠抗氧化功能的影响。方法:以D-半乳糖衰老模型小鼠为研究对象,每天经口灌胃芦笋提取物和阳性对照药(VC),连续给予受试物30d后,测定其脂质过氧化水平和抗氧化酶活力。结果:芦笋提取物可以提高氧化应激小鼠血浆和肝脏中GSH、SOD、GSH-PX、T-AOC活性(p<0.05),显著降低其血浆和肝脏中MDA的含量(p<0.05)。结论:芦笋提取物有助于增强氧化应激小鼠的抗氧化能力。
Objective：To study the antioxidation functional effect of Asparagus extracts on oxidative stress model mice.Methods：Experimental aging mice molded with D-gal,then the mice were gavaged with different dosage of asparagus extracts and VC respectively everyday.30d later,the lipid peroxide level and the antioxidant enzymes vitality were conducted.Results：Asparagus extracts significantly increased GSH,SOD,GSH-PX and T-AOC activity levels（p0.05） in plasma and liver,and significantly decreased MDA content in plasma and liver（p0.05）.Conclusion：Asparagus extracts could improve the antioxidant capacity of oxidative stress model mice.
出处
《食品工业科技》
CAS
CSCD
北大核心
2012年第22期365-368,共4页
Science and Technology of Food Industry
基金
中央高校基本科研业务费专项资金资助项目(JUSRP111A35
JUSRP21115)
科技部农业成果转化资金项目(2010GB2A200024)
秦皇岛市科学技术与发展计划项目(20121107001)
江苏高校优势学科建设工程资助项目
关键词
芦笋提取物
抗氧化
氧化应激模型
小鼠
Asparagus extracts
antioxidant
oxidative stress model
mice
