乳酸菌细菌素纯化技术的检测及研究进展

Detection technique of bacteriocin from lactic acid bacteria and research advance in separation and purification technology

细菌素可以抑制大量的食品源腐败菌和致病菌,因此,近年来受到国内外广大学者的关注,其中乳酸菌细菌素因其安全性尤为受到关注。然而要使细菌素更好地应用到生物技术领域,揭示乳酸菌细菌素的生物化学结构和作用位点就显得尤为重要,而这又是建立在乳酸菌细菌素的纯化基础上。文章结合乳酸菌细菌素纯化技术及检测的最新研究进展,讨论乳酸菌细菌素在食品和医疗领域的发展潜力。

Bacteriocins can be against numerous foodborne pathogen and spoilage organisms,hence researchers at home and aboard are interested in bacteriocins,especially,bacteriocin from lactic acid bacteria（LAB） are focused most.However,for bacteriocin could be applied to biotechnological fields better,it is essential to illuminate its biochemical structure and its mode of action,which needs that bacteriocins is purified to homogeneity.The main technologies used for the purification and detection of numerous bacteriocins was described,the exploration of bacteriocins potential in LAB was also discussed.