140所医院ICU医院感染病原菌分布及耐药性分析

Distribution and drug resistance of pathogens causing nosocomial infections in ICU of 140 hospitals

目的通过对ICU进行目标性监测,了解ICU住院患者医院感染病原菌的分布及耐药性,提出控制措施。方法回顾性统计分析2011年1-12月入住ICU患者医院感染常见病原菌及耐药性,进行。结果 1年中全省140所医院所有医院感染病例共获得各种病原菌10765株,以革兰阴性杆菌为主6864株占63.76%,革兰阳性菌明显减少仅有2566株占23.84%,真菌1335株占12.4%;检出病原菌对临床常用抗菌药物均有不同程度的耐药性,多药耐药呈增加趋势。结论降低ICU医院感染发生率,减少ICU医院感染病原菌的增加,合理使用抗菌药物是今后医院感染工作的重要内容。

OBJECTIVE To perform the targeted monitoring of the ICU and understand the distribution and drug resistance of the pathogens isolated from the hospitalized patients in ICU so as to put forward the control measures.METHODS The common pathogens causing nosocomial infections in the patients who enrolled the ICU from Jan to Dec 2011 were statistically analyzed,the drug resistance was observed.RESULTS A total of 10 765 strains of pathogens were isolated from 140 hospitals within one year,among which there were 6864（63.76%） strains of gram-negative bacilli,2566（23.84%） strains of gram-positive bacteria,and 1335（12.4%） strains of fungi.The isolated pathogens varied in the drug resistance to the commonly used antibiotics.The multidrug-resistant bacteria kept an increasing upward tendency.CONCLUSION It is crucial to the infection control to reduce the incidence of nosocomial infections in ICU,decrease the pathogens causing nosocomial infections,and use antibiotics reasonably.