小剂量氨茶碱口服治疗慢性阻塞性肺疾病的效果

Effect of Small Dose Aminophylline by Oral in the Treatment of Chronic Obstructive Pulmonary Disease

目的探讨小剂量氨茶碱口服治疗慢性阻塞性肺疾病的效果。方法选取我医院中心2009年12月至2011年11月慢性阻塞性肺疾病患者46例,随机分为治疗组和对照组,治疗组患者口服100mg氨茶碱片,每日2次,同时进行肺康复训练,对照组患者仅进行肺康复训练。观察比对两组治疗1周后效果。结果治疗组和对照组治疗前后肺疾病均有好转,各项功能指标均有改善,治疗组优于对照组,P<0.05,具有统计学意义。结论肺康复训练与小剂量氨茶碱口服治疗慢性阻塞性肺疾病的效果显著,值得临床推广。

Objective To explore the effect of small dose aminophylline by oral in the treatment of chronic obstructive pulmonary disease. Methods 46 patients with chronic obstructive pulmonary disease in our hospital from December 2009 to November 2011 were selected and divided into two groups. 23 cases of the treatment group were treated with pulmonary rehabilitation training and 100 mg aminophylline by oral twice a day; and 23 cases of the control group were only treated with pulmonary rehabilitation training. The curative effect after one week was compared between the two groups. Results The lung function and each function index of patients in both groups were improved after treatment. The treatment group was superior to the control group, and the difference was statistically significant （P 〈0.05）. Conclusions Pulmonary rehabilitation training and small dose aminophylline by oral has significant effect in the treatment of chronic obstructive pulmonary disease, which is worthy of clinical application.