低剂量CT对肺癌早期筛查的研究

Study of low-dose computed tomography for early diagnosis of lung cancer

目的研究在肺癌高危人群中低剂量CT(LDCT)对肺癌早期诊断的可行性。方法 1019例受试者随机分入LDCT组(411例)和胸片(CXR)组(608例)。结果 LDCT组与CXR组分别有55例(13.4%)和13例(2.1%)非钙化结节,LDCT组有4例确诊为肺癌(3例Ⅰ期,1例Ⅲ期),CXR组2例(均为Ⅲ期)确诊为肺癌。结论 LDCT比CXR筛选阳性率高,更有利于发现早期肺癌。

Objective To determine the feasibility of low - dose computed tomography （LDCT） for early diagnosis of lung canc- ers in individuals at high risk of lung cancer. Methods 1019 Participants were randomly assigned to two groups uundcrgoing LDCT （411 participants） and chest radiography （608）. Results The rate of positive screening tests was 14. 3% with LDCT and 2. 1% with radio- graphy. 4 cases of lung cancer were in the LDCT group and 2 case in the CXR group. Condusions Through LDCT, more positive cases can be detected and more power in early diagnosis of lung cancer.