液基细胞学技术在胸腹水检验中的应用

Application of Liquid-based cytology technology in the research of pleural effusion and the ascites

目的探讨液基细胞学(Liquid-based cytology)技术在胸腹水检验中的应用价值。方法将40例胸腹水标本分别采用传统细胞涂片法与液基细胞学方法进行检查,将两组结果进行比较,数据采用卡方检验。结果本次试验传统涂片确诊癌4例(10%),细胞薄层技术制片确诊癌12例(30%),两种制片方法阳性细胞检出率差异有统计学意义(P<0.05)。结论细胞薄层技术能够提高被检胸腹水的涂片质量,大大提高了恶性细胞的检出率,为临床治疗提供了可靠的诊断依据。

Objective To study the value of Liquid-based cytology technology in test of pleural effusion and the ascites.Methods 40 cases of pleural effusion and the ascites were detected simultaneously and respectively using Liquid-based cytology and traditional cells smears.The consequence of the two groups were compared and analyzed with chisquare test.Results Of the 40 cases,the carcinomatous cases diagnosed by the methods of traditional cells smears were 4（10%）,The carcinomatous cases diagnosed by the Liquid-based cytology were 12（30%）.There was obvious difference in the detection rate of the malignant cells between them（P0.05）.Conclusion Liquid-based cytology methods have improving the smears quality of pleural effusion and the ascites,and improving the rate of diagnose malignant cells obviously,to provide reliable evidence of diagnosis on clinical therapy.