微泵气管内给药治疗气管切术后呼吸系统真菌感染疗效分析

Respiratory System Mycotic Infection after Tracheotomy Treatment by Local Application through Minipump

目的:探讨微泵气管内给药治疗气管切开术后呼吸系统真菌感染的有效性。方法:将60例气管切开术后诊断为呼吸系统真菌感染的患者随机均分为两组,A组:采用单纯静脉给药;B组:采用静脉给药加气管内持续给药。分别统计两组患者在治疗终点时的有效率,疗效比较采用百分率表示,两组患者有效率的比较采用x2检验,P<0.05表示差异有统计学意义。结果:静脉给药加气管内给药组的总有效率为73.7%,单纯静脉给药组的总有效率为53.3%,两者比较差异有统计学意义(x2=4.8,P<0.05)。静脉给药加气管内给药治疗气管切开术后呼吸系统真菌感染的疗效明显优于单纯静脉治疗。结论:静脉给药加气管内持续给药是治疗气管切开术后呼吸系统真菌感染的有效方法。

ABSTRACT Objective： To determine the effectiveness of local application through minipump treatment on the respiratory system mycotic infection after Tracheotomy. Methods： Sixty patients with the respiratory system mycotic infection after Traeheotomy were randomly divided into two groups： Group A （n=30） had only intravenous drip of Itraconazole, and Group B （n=30） had intravenous drip of Itraconazole and local application through Minipump. The therapeutic effect were analyzed and compared by effective power of x2 test. Results： The effective power of Group B was 73.7% and that of Group A was 53.3%. There were significant differences between the two groups in therapeutic effect （x^2=4.8, P〈0.05）. Conclusion： The intravenous drip of Itraconazole and local application through minipump is an effective method for treatment of the respiratory system mycotic infection after Tracheotomy. Key words： Mycotic infection; Respiratory system; Tracheotomy; Local application; Minipump