UV改性DACRON材料抗细菌粘附研究

Modification of Surface of Dacron Materials by UV Irradiation for Prevention of Microbial Adhesion

介绍了对人工心瓣植入用涤纶布 (Dacron)表面以紫外辐照为主进行接枝改性的方法 ,在其材料表面引入聚乙二醇 (Polyethlene glycol,PEG) ,利用 PEG的“化学放大”作用再引入肝素 (Heparin,Hep) ,改性后的材料抗细菌粘附效果显著 ,与未改性材料相比 ,细菌粘附减少 90 %。

UV irradiation grafting method was used to modify the surface of Prosthetic Valve materials(Dacron) for prevention of bacteria adhesion, and PEG was introduced to the surface of Dacron by this method. The result showed that the chemical magnifying effect of PEG improved the grafting of heparin on the material surface. This method can obviously reduce the number of adherent bacteria.