低钾型周期性瘫痪58例临床分析

58 cases of hypokalemic periodic paralysis clinical analysis

目的探讨低钾型周期性瘫痪的临床特点、诊治和预防方法。方法回顾性分析我院收治的58例低钾型周期性瘫痪患者的临床资料。结果 58例低钾型周期性瘫痪患者主要表现为四肢肌无力,近端、下肢较严重,双侧膝腱反应减退或者消失。辅助检查提示血清钾水平普遍低于正常值,心电图有低钾型改变,部分患者T3、T4升高,肌电图有电位幅度降低表现。采取口服和静脉补钾方法治疗后,全部患者均痊愈。结论低钾型周期性瘫痪可根据其临床表现和辅助检查结果进行诊断,治疗主要采用口服和静脉补钾方法,多数可痊愈,但是应该加强预防,减少诱发几率。

Objective To investigate the clinical characteristics of hypokalemic periodic paralysis,treatment and prevention methods.Methods Retrospective analysis of 58 cases of hypokalemic periodic paralysis in patients with the clinical data.Results 58 cases of hypokalemic periodic paralysis patients with mainly limb weakness,proximal lower limb is more serious and bilateral patellar tendon response diminished or disappeared.Auxiliary examinations showed that the serum potassium level is generally lower than normal,hypokalemic changes in ECG,some patients＇T3 and T4 increased and EMG potential amplitude reduced.Take oral and intravenous potassium method of treatment and all patients were cured.Conclusion Hypokalemic periodic paralysis＇ diagnosis can be according to the results of its clinical manifestations and laboratory examinations,treatment using the method of oral and intravenous potassium,the majority can be cured,but should be strengthened to prevent,reduce the induced probability.