复方甘草酸苷片及卤米松乳膏联合窄谱中波紫外线治疗白癜风疗效分析

Analysis of the effect of compound glycyrrhizin and halometasone cream combined with narrow band ultraviolet therapy vitiligo

目的观察分析复方甘草酸苷片及卤米松乳膏联合窄谱中波紫外线治疗白癜风疗效,总结其临床治疗经验及临床应用价值。方法选取该院2011年2月—2012年7月白癜风的患者104例,随机分为观察组与对照组,各为52例,观察组使用复方甘草酸苷片及卤米松乳膏联合窄谱中波紫外线治疗,对照组使用卤米松乳膏联合窄谱中波紫外线治疗,观察对比两组治疗效果,进行统计学分析。结果观察组痊愈27例,显效13例,有效9例,无效3例,无不良反应出现,总有效率为76.9%;对照组痊愈21例,显效8例,有效17例,无效6例,不良反应出现5例,总有效率为55.8%,两组治疗效果及不良反应发生率比较差异有统计学意义(P<0.05),具有统计学意义。结论复方甘草酸苷片及卤米松乳膏联合窄谱中波紫外线治疗白癜风疗效显著,明显优于单纯使用卤米松乳膏联合窄谱中波紫外线治疗,能够显著改善临床症状,提高治愈率,降低长期使用激素带来的副作用,无明显的不良反应,安全可靠,值得临床合理推广。

Objective Observation of the effect of Compound Glycyrrhizin and Halometasone Cream Combined with narrow band ultraviolet therapy vitiligo, summarizes the clinical treatment experience and application value. Method In cases of vitiligo patients were selected from February 2011 to July 2012 in our hospital, were randomly divided into the observation group andthe control group, 52 cases in each group, to observe theuse of Compound Glycyrrhizin and Halometasone Cream Combinedwithnarrow bandultraviolet therapy,The control group uses Halometasone Cream Combined with narrow-band ultraviolet treatment, observation and comparison of two treatment, statistical analysis. Results The patients in the observation group 27 caseswere cured, 13 cases, effective in 9 cases, ineffective in3 cases, and no adverse reaction cases,The total effective ratewas 76.9%; the control group patients 21 cases were cured, 8 cases, effective in 17 cases, 6 cases ineffective, the occurrence of adverse reactions in 5 cases, the total effective rate was 55.8%, the two treatment groups and the incidence of adverse reactions compared with obvious difference （P0.05）,Statistical significance. Conclusion Compound Glycyrrhizinand Halometasone Cream Combined with narrow band ultraviolet therapy vitiligo effect significantly, in comparison with theuse of Halometasone Cream Combined with narrow-band ultraviolettreatment effect is good,It can significantly improve the clinical symptoms of the patients and improve the cure rate, decrease the long-term use of hormone producing side effects, adverse reactions rarely occurs, safe and reliable, is worth the clinical reasonable promotion.