硒化壳聚糖理化性质和分子结构的研究

STUDY ON THE PHYSICAL AND CHEMICAL PROPERTIES AND THE MOLECULAR STRUCTURE OF SELENO-CHITOSAN

运用高效凝胶色谱 (HPGPC)、乌氏粘度计、XYG- 1 1 0型多功能原子荧光仪、常规溶剂和 WZZ- 1自动指示旋光仪等方法对本实验室制备的硒化壳聚糖的理化性质进行测定 ,结果表明 :硒化壳聚糖的分子量为3448;特性粘度为 99;室温干燥放置 1年 ,硒化壳聚糖保持稳定 ;硒化壳聚糖在水中可溶 ,而且溶解度随温度升高而增加 ,但在有机溶剂中基本不溶 ;硒化壳聚糖在 2 5℃时的旋光度为 - 1 4。通过紫外光谱、红外光谱、氢谱 (1 HNMR)和碳谱 (1 3 CNMR)的测定分析 ,确定亚硒酸根是连接在壳聚糖分子中 C2 位的氨基上和 C6位的羟基上。

In this paper,the physical and chemical properties of seleno-chitosan prepared by our lab were investigated ,and compared with that of chitosan and sulfonationed chitiosan.Moreover,the causes of what resuited from the diference were analized.It is primarily confirmed that SeO 2- 3 is attached to C 2 amino and C 6 hydroxyl of chitosan according to the results of UV,IR, 1HNMR,and 13 CNMR.