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利妥昔单抗治疗婴儿难治性自身免疫性溶血性贫血伴假性血小板减少一例报告附文献复习 被引量：2

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摘要 自身免疫性溶血性贫血（AIHA）系体内B淋巴细胞免疫调节紊乱，产生自身抗体和（或）补体，并结合于红细胞膜上，致红细胞破坏加速而引起的一组溶血性贫血。婴儿难治性AIHA症状重，病程迁延，病死率高，治疗目标是迅速控制溶血。利妥昔单抗治疗成人原发免疫性血小板减少症（ITP）、AIHA及Evans综合征安全有效。
作者 安文彬 郭晔 王书春 杨文钰 衣晓丽 戚本泉 竺晓凡
机构地区 中国医学科学院、北京协和医学院血液学研究所、血液病医院儿童血液病诊疗中心
出处 《中华血液学杂志》 CAS CSCD 北大核心 2012年第11期957-959,共3页 Chinese Journal of Hematology
关键词 自身免疫性溶血性贫血 单抗治疗 假性血小板减少 难治性 利妥昔 文献复习 婴儿 免疫性血小板减少症
分类号 R725.5 [医药卫生—儿科]
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参考文献19

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同被引文献16

  • 1赵湜,王红祥,李菁媛,毛红,邹萍.调节性T细胞在慢性特发性血小板减少性紫癜中的作用[J].中华血液学杂志,2006,27(3):203-205. 被引量：17
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  • 10Marson A, Kretschmer K, Frampton GM, et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation [ J ]. Nature ,2007,445 (7130) :931-935.

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中华血液学杂志
2012年 第11期

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