摘要
心血管疾病已成为现代社会人类死亡的首要病因。本文综述了近年来核因子-κB(NF-κB)在心血管疾病的发病、进展和治疗方面的研究进展。可以预见,NF-κB将有可能成为心血管疾病治疗中的新途径和新靶向。
Cardiovascular disease is the primary cause of morbidity and mortality in modem society all over the world. The present article reviewed the recent research on the correlation between NF-κB and the onset, progression and treatment of cardiovascular disease. It can be expected that NF-κB signaling pathway will provide an important therapeutic pathway and target for cardiovascular disease.
出处
《同济大学学报(医学版)》
CAS
2012年第5期119-124,共6页
Journal of Tongji University(Medical Science)
基金
国家自然科学基金(30500681
30973845)
上海市科委中医药现代化项目(09dZ1975000)
上海市卫生局中医药科研基金(2008L012A)
关键词
核因子-ΚB
炎症
心血管疾病
nuclear factor-κB
inflammation
cardiovascular disease