葡萄膜黑色素瘤治疗争论的病理基础

The pathological basis of the argument in the treatment of melanoma of the uveal tract

葡萄膜黑色素瘤为成年人眼内常见的恶性肿瘤。不管采取何种治疗手段，50％的患者会死于致死性的转移。眼球摘除为其主要和最基本的治疗手段。长期以来一直存在争论：葡萄膜黑色素瘤眼球摘除是否加速了转移死亡的发生？本文关注这个问题，就争论的焦点结合病理及实验研究的一些进展进行了讨论。

Melanoma of the uveal tract is most common primary intraoeular cancer in adults. Approximately 50% of patients with uveal melanoma died from metastasis, irrespective of the type of treatment. Enucleation was the primary form of treatment and the best option. Whether the enucleation of the eye containing urea1 melanoma accelerates metastatic death has long been a controversial topic. The combination of pathological and some experimental studies in progress concerning this contentious topic is discussed in the current article.