新型光学低相干反射仪Lenstar与IOLMaster测量人工晶状体度数的比较研究

Comparison of Lenstar and IOLMaster for intraocular lens power calculation

【摘要】目的比较新型光学低相干反射仪Lenstar与IOLMaster测量厶工晶状体（IOL）度数的一致性和准确性。方法前瞻性对照研究。同一观测者分别应用光学低相干反射仪Lenstar和IOLMasterV5．4测量98例白内障患者157只眼的眼轴长度（AL），角膜曲率值（Km）和前房深度（ACD），比较两种仪器测量眼前节参数的相关性和差异性，并且比较分别使用4种IOL公式（SRK／T、HolidayI、HofferQ和Haigis）计算的IOL度数，目标屈光度设定为正视眼。两组数据间比较采用t检验或Wilcoxon检验，两种仪器测量数据进行IOL度数计算的一致性研究采用Bland．Ahman法。结果Lenstar和IOLMaster测量AL的平均值分别为（23．65±1．17）mm和（23．65±1．16）mm，Km值分别为（44．15±1．58）D和（44．17±1．58）D，差异均无统计学意义（P〉0．05），ACD分别为（3．09±0．41）mm和（3．05±0．41）mm，差异有统计学意义（P=0．001）。两仪器测量同一参数结果均具有高度相关性（所有r〉0．9，P〈0．001）。两种仪器应用4种IOL公式计算结果一致性较好，其中应用SRK／T公式计算差异最小，1-Iaigis公式差异相对较大。结论应用Lenstar测量眼球生物参数具有准确性、非接触性、操作简便、安全而且患者易于接受的优点，为我们提供了白内障术前准确可靠的数据，在白内障人群中与IOLMaster比较具有较好的一致性。

Objective To evaluate the precision of Intraocular Lens （IOL） power calculation using a new optical low-coherence reflectometry biometer （Lenstar） and compare the results with those obtained with IOLMaster. Methods It was a prospective controlled study. Biometry measurements in 157 eyes of 98 cataract patients were performed by the same examiner with Lenstar and IOLMaster. Axial length （AL） , corneal keratometry readings （Kin） , and anterior chamber depth （ ACD ） were obtained. Correlation and differences of biometry measurements obtained with two biometers were made. Intraocular Lens power were calculated using 4 formulas and the corresponding IOL constants, the target was emmetropia. Then statistical analysis was proceeded. Results Axial length were （ 23.65 ± 1.17 ） mm and （ 23.65±1.16 ） mm respectively , Kin（44. 15 ±1.58）D and （44. 17 ±1.58）D respectively by Lenstar and IOLMaster and no statistical differences were found （ P 〉 0. 05 ） . ACD were （ 3.09 ± 0. 41 ） mm and （ 3.05± 0.41 ） mm respectively by Lenstar and IOLMaster and there was statistical difference between them（ P = 0. 001 ）. All biometry measurements showed good linear correlation（ r 〉 0. 9,P 〈 0. 001 ）. IOL power calculations with biometry values between Lenstar and IOLMaster using the 4 formulas showed good agreement. The least difference was obtained with formula SRK/T and the most with formula Haigis. Conclusions Lenstar can provide precise and noncontact biometry measurements easily and safely, which are welcome by patients. Providing precise and reliable biometry measurements of cataract patients for Intraocular Lens power calculation, it shows good agreement with IOLMaster and the two biometers can be interchanged.