摘要
目的研究冠心病患者的CD41水平,以及冠脉内介入治疗(PCI)术对CD41水平的影响。方法测定所有患者(包括258例冠心病患者及98例非冠心病患者)的CD41水平。行PCI术者(235例)及仅行冠状动脉造影(CAG)的患者(121例)术前及术后2h的CD41水平。结果冠心病者的CD41水平明显高于非冠心病者。CD41水平在PCI术后2h显著高于术前(P<0.05),而在仅行CAG术的患者CD41水平无明显变化(P>0.05)。结论冠心病患者的血小板活性高于非冠心病者,PCI术可促进血小板激活。
Objective To observe CD41 levels in patients with coronary heart disease and to investigate the influence of percutaneous coronary artery interventional therapy （PCI） on CD41 levels. Methods The CD41 levels in 258 patients with coronary heart disease （ CHD group） and 98 patients with non-coronary heart disease （NCHD group） were detected,and the CD41 levels in 235 patients who received PCI and 121 patients who received coronary angiogram（CAG） were detected by flow cytometry before and 2 hours after operation. Results The CD41 levels in CHD group were significantly higher than those in NCHD group. The CD4L levels at 2 hours after PCI were significantly higher than those before operation（ P 〈0. 05 ）, however, there was no significant difference in CD41 levels in the patients who received simple CAG before and after PCI （ P 〉 0.05）. Conclusion The activity of platelet in patients with CHD is higher than that in patients with NCHD, and PCI can promote platelet activation.
出处
《河北医药》
CAS
2012年第19期2890-2891,共2页
Hebei Medical Journal
基金
广东省卫生厅科技项目(编号:B2003123)
关键词
冠心病
经皮冠状动脉介入治疗
CD41
coronary heart disease
percutaneous coronary artery interventional therapy
CD41
