三种不同检查方法在胃食管反流病诊断中的应用比较

The allicaton comparison of three different inspection methods in the diagnosis of gastroesophageal reflux disease

目的:探讨电子胃镜、24 h食管pH值监测及胃食管反流病(GERD)Q评分三种方法在GERD诊断中的临床应用价值。方法:将于2011年4月—2012年6月因烧心、反酸等症状就诊于消化科门诊的120例患者随机分为胃镜组、24 h食管pH值监测组及GERD Q评分组,每组40例,分别接受电子胃镜、24 h食管pH值监测及GERD Q问卷评分,比较分析各种方法对GERD的检出情况。结果:24 h食管pH值监测组40例患者中病理性反流者19例,生理性反流者5例,GERD阳性率显著高于胃镜组及GERD Q评分组,差异具有统计学意义(P<0.05);胃镜组与GERD Q评分组之间差异无统计学意义(P>0.05)。结论:24 h食道pH值监测可以对食管内反流情况进行实时、动态监测,为GERD的临床诊断及不同类型的反流治疗方案提供客观、准确的依据。

Objective：To investigate the clinical using value of electron gastroscopy,esophageal pH monitoring 24 h and gastroesophageal reflux disease（GERD） Q scores in the diagnosis of GERD.Methods：From April 2011 to June 2012 because of heartburn,acid reflux symptoms presenting to hospital gastroenterology clinic：120 cases were randomly divided into group 24 h esophageal pH monitoring group,gastroscope group and GERD Q score group,40 cases in each group,respectively,to accept electronic gastroscope,24 h esophageal pH monitoring and GERD Q questionnaire score,comparative analysis of various methods the detection of GERD.Results：24 h esophageal pH monitoring in 40 cases of pathological reflux in 19 cases,physiologic reflux in 5 cases,the positive rate of GERD was significantly higher than that of gastroscope group and GERD Q score group,the difference was statistically significant（P〈0.05）;gastroscope group and GERD Q score between the groups had no significant difference（P〈0.05）.Conclusion：24 h esophageal pH monitoring of esophageal reflux in real-time,dynamic monitoring,for clinical diagnosis of GERD and different types of reflux treatment program provides objective,accurate basis,is worth in clinical application.