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活性创面覆盖物的研究和应用 被引量：3

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摘要 大面积烧伤皮肤屏障功能丧失是造成烧伤后休克、感染、多器官功能障碍综合症（Multiple organ dysfunction syndrome,MODS）、创面愈合不良、瘢痕形成的根本原因,尽早覆盖创面对于减少并发症、降低死亡率具有重要意义。
作者 郇京宁
机构地区 上海交通大学医学院附属瑞金医院烧伤整形科
出处 《中华损伤与修复杂志（电子版）》 CAS 2012年第3期4-6,共3页 Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
关键词 创面覆盖物 多器官功能障碍综合症 应用 活性 大面积烧伤 功能丧失 皮肤屏障 愈合不良
分类号 R644 [医药卫生—外科学]
  • 相关文献

参考文献11

  • 1Griffiths M, Ojeh N, Livingstone R, et al. Survival of Apligraf in acute human wounds [ J ]. Tissue Eng, 2004,10 ( 7-8 ) : 1180-1195.
  • 2Macri L, Clark RA. Tissue engineering for cutaneous wounds: selecting the proper time and space for growth factors, cells and the extracellular matrix [ J ]. Skin Pharmacol Physiol, 2009,22 ( 2 ) : 83 -93.
  • 3Groeber F, Holeiter M, Hampel M, et al. Skin tissue engineering-In vivo and in vitro applications[ J]. Advanced Drug Delivery Reviews, 2011, 63(4-5) :352-366.
  • 4Fujita T, Miyagawa S, Ezoe K, et al. Skin graft of double transgenic pigs of N-acetylglucosaminyhransferase Ⅱ I ( GnT- III ) and DAF (CD55) genes survived in cynomolgus monkey for 31 days [J]. Transplant Immunology ,2004, (13) : 259-264.
  • 5Tonello C,Vindigni V,Zavan B, et al. In vitro reconstruction of an endothelialized skin substitute provided with a microcapillary network using biopolymer scaffolds[J]. FASEB J, 2005,19 ( 11 ) : 1546- 1548.
  • 6Harrison CA, Heaton MJ, Layton CM, et al. Use of an in vitro model of tissue-engineered human skin to study keratinocyte attachment and migration in the process of reepithelialization [ J ]. Wound Repair Regen, 2006,14(2) :203-209.
  • 7Lootens L, Brusselaers N, Beele H, et al. Keratinocytes in the treatment of severe burn injury: an update[ J]. Int Wound J, 2012. doi : 10.1111/j. 1742-481X. 2012. 01083. x.
  • 8Dezutter-Dambuyant C,Black A, Bechetoille N,et al. Evolutive skin reconstructions : from the dermal collagen-glycosaminoglycan- chitosane substrate to an immunocompetent reconstructed skin [J]. Biomed Mater Eng, 2006,16 (4 Suppl) : S85-94.
  • 9Lee JH, Kim JE, Kim B J, et al. In vitro phototoxicity test using artificial skin with melanocytes [ J ]. Photodermatol Photoimmunol Photomed, 2007,23 ( 2-3 ) :73-80.
  • 10Cerqueora MT, Marques AP, Reis RL. Using stem cells in skin regeneration : possibilities and reality [ J ]. Stem Ceils Dev, 2012, 21 (8) :1201-1214.

同被引文献19

  • 1辛国华,曾逃方.深度烧伤创面的处理现状及有关问题思考[J].中华临床医师杂志（电子版）,2012,6(18):12-14. 被引量：10
  • 2王钰,夏照帆.永久性皮肤替代物的现行模式和发展方向[J].中华创伤杂志,2006,22(2):95-97. 被引量：2
  • 3陈壁,贾赤宇.复合皮移植[M].西安:第四军医大学出版社,2004,10-12.
  • 4Gosk J. Skin substitutes-the present and the future[ J]. Polim Med,2012,42(2) : 109-114.
  • 5Greaves NS, Igbal SA, Baguneid M, et al. The role of skinsubstitutes in the management of chronic cutaneous wounds [ J ].Wound Repair Regen,2013,21(2) : 194-210.
  • 6Kim H, Son D, Choi TH, et al. Evaluation of an amnioticmembrane-collagen dermal substitute in the management offull-thickness skin defects in a pig [ J]. Arch Plast Surg, 2013 , 40(1): 11-18.
  • 7Hamuy R, Kinoshita N, Yoshimoto H, et al. One-stage,simultaneous skin grafting with artificial dermis and basic fibroblastgrowth factor successfully improves elasticity with maturation of scarformation [J]. Wound Repair Regen, 2013,21(1) : 141-154.
  • 8Leonardi D, Oberdoerfer D,Fernandes MC, et al. Mesenchymalstem cells combined with an artificial dermal substitute improverepair in full-thickness skin wounds [ J]. Bums, 2012,38(8):1143-1150.
  • 9潘云川,徐家钦,袁素,梁尊鸿,陈思环,陈茹妹,林思燕.异体脱细胞真皮基质加自体刃厚皮复合移植远期随访评价[J].中华烧伤杂志,2010,26(6):439-443. 被引量：12
  • 10陈凯.皮肤软组织扩张术应用于烧伤整形效果观察[J].中国医学创新,2012,9(14):42-43. 被引量：14

引证文献3

二级引证文献22

中华损伤与修复杂志（电子版）
2012年 第3期

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