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临床评分结合D-二聚体检测对急性脑梗死患者下肢深静脉血栓的诊断价值 被引量:6

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摘要 目的探讨临床评分结合D-二聚体检测对急性脑梗死患者下肢深静脉血栓(LDVT)的诊断价值。方法急性脑梗死患者540例,所有患者均按Wells评分量表评分,均行D-二聚体检测及双下肢静脉加压超声检查,比较单独应用Wells评分及D-二聚体检测与Wells评分结合D-二聚体检测诊断急性脑梗死患者LDVT的敏感性、特异性、阳性似然比、阴性似然比。结果经下肢静脉加压超声诊断LDVT 42例(7.8%)。若以Wells评分中度可能及高度可能为阳性结果,Wells评分诊断脑梗死患者LDVT的敏感性、特异性、阳性似然比、阴性似然比分别是:81.0%、48.2%、1.56、0.39。若以D-二聚体≥500 ng/ml为阳性结果,D-二聚体诊断脑梗死患者LDVT的敏感性、特异性、阳性似然比、阴性似然比分别是:78.6%、75.5%、3.21、0.28。若以Wells评分中、高度可能同时D-二聚体≥500 ng/ml为阳性结果,Wells评分低度可能同时D-二聚体<500 ng/ml为阴性结果,Wells评分结合D-二聚体诊断脑梗死患者LDVT的敏感性、特异性、阳性似然比、阴性似然比分别是:93.1%、71.1%、3.22、0.10。结论 Wells评分结合D-二聚体检测对脑梗死患者LDVT诊断的准确性较高,Wells评分低度可能同时D-二聚体阴性可较为安全地排除LDVT的诊断。
出处 《河北医药》 CAS 2012年第16期2443-2445,共3页 Hebei Medical Journal
基金 广东省医学科研基金项目资助(编号:A2010685)
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