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帕瑞昔布钠用于腹腔镜胆囊切除术术后镇痛效果观察 被引量:3

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摘要 切口痛与牵涉痛是导致腹腔镜胆囊切除术术后疼痛最为常见的两个原因,它们的性质、强度、持续时间和防治手段有同有异。帕瑞昔布钠可抑制外周环氧合酶-2(COX-2)表达,减少外周前列腺素合成,抑制炎性因子肿瘤坏死因子-α(TNF-α)和白介素-6(IL-6)从而发挥镇痛抗炎作用。
出处 《河北医药》 CAS 2012年第17期2652-2653,共2页 Hebei Medical Journal
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