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子痫前期患者循环内皮细胞数量和血清脂联素水平的变化及临床意义

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摘要 目的探讨血清中循环内皮细胞(CEC)数量和血清脂联素(APN)水平变化与子痫前期(PE)发病及病情轻重程度的相关性。方法将60例PE患者作为试验组,根据其轻重程度又分为轻度PE亚组35例和重度PE亚组25例;另选健康孕晚期妇女40例作为对照组。分别检测各组受试者血清CBC个数和APN变化情况。结果试验组及其亚组CEC数量均少于对照组,且轻度PE亚组少于重度PE亚组,差异均有统计学意义(P<0.05);试验组及其亚组APN水平低于对照组,且轻度PE亚组高于重度PE亚组,差异均有统计学意义(P<0.05)。结论 CBC数量、血清APN水平与PE发病及病情轻重程度有关。
机构地区 河北省人民医院
出处 《临床合理用药杂志》 2012年第34期106-107,共2页 Chinese Journal of Clinical Rational Drug Use
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