注射用兰索拉唑治疗十二指肠溃疡出血的临床疗效观察

Clinical Effect Observe of Treating Ducdenal Ulcer and Hemorrhage with Lansoprazole for Injection

目的评价注射用兰索拉唑治疗十二指肠溃疡出血的疗效及安全性。方法采用随机、盲目、阳性药物平行对照的临床试验。实验组:注射用兰索拉唑;对照组:注射用泮托拉唑。结果 2012年1—4月共有80例患者参加并完成实验。经治疗后,两组治疗十二指肠溃疡出血的有效率相比,差异无统计学意义(P>0.05);两组止血时间相比,差异无统计学意义(P>0.05)。实验组无不良反应发生,对照组不良反应表现为白细胞减少,但两组比较差异无统计学意义(P>0.05)。结论注射用兰索拉唑治疗十二指肠溃疡出血是非常安全的,并且疗效肯定,临床应用价值高。

Aim To use Lansoprazole for injection in the treatment of patients with duodenal ulcerative hemorrhage,and to evaluate its effectiveness and safety.Methods Take a clinical approach featuring random sampling,blinding,positive medications and parallel comparision.testing group：Lasoprazole for injection;control group：Pantoprazole for injection.Results From January 2012 to April 2012,a total of 50 patients enrolled all completed the trial.There was no statistic significantce in hemorrhage effectiveness and hemostasis time between two groups（P0.05）.The testing group has no adverse drug reaction,The control group＇s adversed effects was leucopenia.But there was no statistic significantce in two groups（P0.05）.Conclusion Lasoprazole for injection is effective and safe in treating patients with duodenal ulcerative hemorrhage,and better worthy of clinical application.