90例老年女性卵巢肿瘤的临床分析

Clinical analysis of 90 cases of aged women′s ovarian tumor

目的:探讨老年女性卵巢肿瘤的临床和病理特征,分析其诊断与治疗方法。方法:以经手术确诊的90例≥65岁的老年女性卵巢肿瘤患者为研究对象,对其临床资料及病理结果进行回顾性分析。结果:90例患者中38例有腹胀,腹痛,31例自我触及腹部包快,8例有不规则阴道流血,8例有下腹部不适等非特异性症状,5例无症状;恶性肿瘤66例,占73.3%,交界性肿瘤10例,占11.1%,良性肿瘤14例,占15.6%;恶性和交界性肿瘤CA-125、AFP、CEA明显高于良性肿瘤(P<0.05),恶性肿瘤超声表现多为囊实不均混合回声,形态欠规则,边界欠清晰,大多伴有腹水。结论:老年女性卵巢肿瘤恶性率比较高,应定期进行妇科检查,并结合肿瘤标记物和妇科彩超等影像学特征,作到早期诊断,早期治疗,提高生活质量及延长生存率。

Objective To analyze the clinical and pathologic characteristics of aged women′s ovarian tumor,and explore its diagnosis and treatment.Method The clinical data and pathologic results were analyzed retrospectively in 90 patients with ovarian tumor over 65 years old.Results Among the 90 cases,38 had abdominal distention or abdominal pain,31 had self-conscious abdominal mass,8 had colporrhagia,8 had symptoms such as hypogastrium discomfort,and 5 had no symptoms.Among them,66 cases（73.3%） were malignant ovarian tumors,10（11.1%）were borderline tumors and 14（15.6%）were benign tumors.The positive rates of serum CA-125,AFP and CEA were significantly higher in malignant and borderline cases（P0.05） than in benign ones.Ultrasound examination showed that the malignant ovarian tumors were most cyst-parenchymatous image,the forms were less under rules,and the boundary was less clear,and most of them always showed ascites.Conclusion Aged women′ ovarian tumor has higher incidence of malignancy.These women should be examined regularly.Tumor markers and image technique are all important in the early diagnosis.Once confirmed,early treatment are needed,in order to improve the quality of life and extend survival.