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高IgM综合征研究进展 被引量：10

Study Progress of Hyper - Immunoglobulin M Syndromes
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摘要 高IgM综合征是一种较罕见的原发性免疫缺陷病,主要表现为反复感染,血清IgG、IgA和IgE明显降低,IgM水平正常或升高,B淋巴细胞数正常。近年来,随着分子生物学的发展,发现了越来越多的高IgM综合征类型,在其诊断和治疗方面也取得了新的进展。
作者 陈同辛 金莹莹
机构地区 上海交通大学医学院附属上海儿童医学中心儿内科过敏/免疫诊疗部
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2012年第21期1624-1628,共5页 Journal of Applied Clinical Pediatrics
关键词 高IGM综合征 CD40配体 中性粒细胞减少
分类号 R725.9 [医药卫生—儿科]
  • 相关文献

参考文献25

  • 1Al - Herz W,Bousfiha A,Casanova JL, et al. Primary immunodeficiencydiseases:An update on the classification from the international union ofimmunological societies expert committee for primary immunodeficiency[J]. Front Immunol,2011 ,2 :54.
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  • 3Imai K, Slupphaug G, Lee WI, et al. Human uracil - DNA glycosylasedeficiency associated with profoundly impaired immunoglobulin class -switch recombination[ J]. Nat Immunol,2003 ,4( 10). : 1023 - 1028.
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  • 5Imai K,Catalan N,Plebani A,et al. Hyper - IgM syndrome type 4 with aB lymphocyte - intrinsic selective deficiency in Ig class - switch recom-bination[ J]. J Clin Invest,2003 ,112(1). : 136 - 142.
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二级参考文献17

  • 1Evelina Mazzolari,Donatella Martiis,Concetta Forino,Arnalda Lanfranchi,Silvia Giliani,Roberto Marzollo,Paolo Airò,Luisa Imberti,Fulvio Porta,Luigi D. Notarangelo.Single-center analysis of long-term outcome after hematopoietic cell transplantation in children with congenital severe T cell immunodeficiency[J]. Immunologic Research . 2009 (1-3)
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  • 6Buckley RH,Schiff SE,Schiff RI,et al.Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. New England Journal of Medicine, The . 1999
  • 7Rosen FS,Wedgwood RJ,Eibl M,et al.Primary immunodeficiency diseases: report of a WHO scientific group. Clinical and Experimental Immunology . 1997
  • 8Borghans JA,Bredius RG,Hazenberg MD,et al.Earlydeterminants of long-term T-cell reconstitution afterhematopoietic stem cell transplantation for severe combinedimmunodeficiency. Blood . 2006
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  • 10Grunebaum.E,Mazzolari E,Porta F,et al.Bone Marrow Transplantation for Severe Combined Immune Deficiency. The Journal of The American Medical Association . 2006

共引文献8

同被引文献55

  • 1Davies E G, Thrasher A J. Update on the hyper immunoglobulin M syndromes[J]. Br J Haematol,2010,149(2):167-180.
  • 2Lee W I, Torgerson T R, Schumacher M J,et al. Molecular analysis of a large co- hort of patients with the hyper Lmmuno- globulin M (IgM) syndrome[J]. Blood, 2005,105(5): 1881 - 1890.
  • 3Jesus A A, Duarte A J, Oliveira J B. Au- toimmunity in hyper-lgM syndrome[J]. Clin Immunol,2008,28(Suppl 1):62-66.
  • 4Tomizawa D, Imai K, Ito S, et al. Allo- geneic hematopoietic stem cell trans- plantation for seven children with X-linked hyper-lgM syndrome: a sin- gle center experience[J]. Am J Hema- tol,2004,76(1):33-39.
  • 5Qamar N, Fuleihan RL. The hyper IgM syndromes [ J ]. Clin Rev Allergy Immunol, 2014, 46(2) : 120 -130.
  • 6A1-Herz W, Bousfdm A, Casanova JL, et al. Primary imnmnodeficieney diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency[ J/OL]. Front Immunol, 2014, 5 : 162.
  • 7Durandy A, Kracker S. Immunoglobulin class-switch recombination deficiencies[J/OL]. Arthritis Res Ther, 2012, 14(4) : 218.
  • 8Peron S, Metin A, Cardes P, et al. Human PMS2 deficiency is associated with impaired immamoglobulin class switch recombination [ J ]. J Exp Med, 2008, 205 ( 11 ) : 2465 - 2472.
  • 9Madkaikar M, Gupta M, Chavan S, et al. X-linked hyper IgM syndrome: clinical, imm~cal and molecular features in patients from India[ J]. Blood Cells Mol Dis, 2014, 53(3) : 99 -104.
  • 10Tsai HY, Yu HH, Chien YH, et al. X-linked hyper-IgM syndrome with CD40LG mutation: two case reports and literature review in Taiwan Residents patients[J]. J Micrebiol Immunol Infect, 2015, 48( 1 ) : 113 -118.

引证文献10

二级引证文献13

实用儿科临床杂志
2012年 第21期

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