摘要
青蒿素是从植物青蒿中分离的具有抗疟作用的倍半萜内酯,在治疗疟疾方面取得了举世瞩目的成绩。但是,世界卫生组织已开始重视由使用青蒿素类药物产生的疟原虫耐药性,并专门制定《全球青蒿素耐药性限制计划》以避免青蒿素耐药范围的扩大。从青蒿素的耐药性现状入手,回顾抗疟药物耐药性的历史进程,以期展望青蒿素类药物发展前景的同时带来新的科学启示。
Artemisinin, a new and a very potent antimalarial drug,is produced by the Chinese medicinal herb Artemisia annual. How- ever,World Health Organization has already pay attention to the antimalarial drug efficacy and drug resistance. The Global plan for arte- misinin resistance containment （GPARC） is a call to stop its spread to new areas. This paper is overviewed recent progress on artemisinin resistance containment, and its development is also prospected.
出处
《中国药物评价》
2012年第4期300-304,共5页
Chinese Journal of Drug Evaluation
关键词
青蒿素
耐药性
世界卫生组织
全球青蒿素耐药性限制计划
Artemisinin
Resistance containment
World Health Organization
Global plan for artemisinin resistance containment
