摘要
目的筛选出最佳的舒通无糖颗粒处方及成型工艺。方法以吸湿率和成型性为指标,筛选出处方中加入辅料的品种、配比及其最佳的成型工艺。结果最佳处方为95%舒通提取物加4%乳糖、1%甘露醇,再辅以15%赤藓糖醇为矫味剂。结论颗粒的成型性好,吸湿性小,溶化性高。
Objective To screen the proper excipients and the preparation process for Shutong Sugar-free Particles.Methods By analyzing the resistance to moisture and moldability,the types and ratio of the excipients and the different preparation process were screened out.Results The most proper preparation was consisted of 95% of the extract of Shutong,4% of lactose,1% of mannit,and then adding 15% of phycite as flavor.Conclusion The optimized granules are characterized with a high resistance to moisture,solubility and moldability.
出处
《中国医药导报》
CAS
2012年第24期121-123,共3页
China Medical Herald
关键词
舒通
无糖颗粒
成型工艺
Shutong
Free-sugar granule
Preparation technology