老年餐后低血压与血管内皮功能相关性研究

Correlation research of the elderly postprandial hypotension and vascular endothelial function

目的探讨老年餐后低血压与血管内皮功能相关性的研究。方法选取270例在我院老年科就诊且明确有老年餐后低血压的患者作为实验组,另选取120例健康者作为对照组。分析实验组患者餐后低血压与血浆中血管性假血友病因子(vwF)、纤维蛋白原(Fbg)的相关性。结果早餐后低血压共120例,中餐后低血压共105例,晚餐后低血压共45例,vwF和Fbg的表达水平分别与对照组相比,差异有统计学意义(P<0.05)。餐后低血压与vwF和Fbg的表达水平具有正相关性(r=0.589、0.603,P<0.05)。结论老年餐后vwF和Fbg的表达水平明显升高,老年餐后低血压与vwF和Fbg具有正相关性,这将为老年餐后低血压的治疗提供新方法和新依据。

Objective To investigate the correlation of the elderly postprandial hypotension and vascular endothelial function.Methods 270 cases of elderly postprandial hypotension in elderly outpatients of our hospital were as experimental group,120 cases of healthy were as control group.Correlation of the elderly postprandial hypotension with von willebrand factor（vwF） and fibrinogen（Fbg） was analyzed.Results Hypotension after breakfast were 120 cases,105 cases were in postprandial hypotension,hypotension after dinner were of 45 cases,expression of vwF and Fbg in the experimental group compared with the control group,all had a significant difference（P 0.05）.The expression of vwF and Fbg with postprandial hypotension had positive correlation（r = 0.589,0.603,P 0.05）.Conclusion The expression of vwF and Fbg in the elderly postprandial were significantly increased,the elderly postprandial hypotension with vwF and Fbg have positive correlation.This can provide new methods and basis for the treatment of elderly postprandial hypotension.