外科手术治疗肝脏局灶结节性增生25例临床分析

Clinical analysis on the surgical operation in 25 patients with focal nodular hyperplasia of the liver

目的探讨运用外科手术治疗肝脏局灶结节性增生的临床效果。方法将本院25例肝脏局灶结节性增生进行手术治疗患者的临床资料进行回顾性分析,另外选取29例采用保守治疗的患者作为对照,比较两组治疗后的效果情况。结果对照组的症状改善率为31.0%,治愈率为51.7%,有1例出现破裂出血转外科手术治疗,并发症发生率为3.4%,观察组的症状改善率为100.0%,治愈率为100.0%,有2例出现感染、胸腔积液等并发症,经过内科治疗后痊愈,并发症发生率为8.0%。两组之间差异有统计学意义(P<0.05)。结论肝脏局灶结节性增生确诊主要依赖于术前或术中病理学检查,对于有明显症状、病灶较大等情况者选择外科手术治疗是首选方法。

Objective To study the clinical effect of surgical operation in focal nodular hyperplasia of the liver.Methods The clinical data of 25 patients with focal nodular hyperplasia of the liver who were treated with surgical operation were retrospectively analyzed,and 29 patients who were treated with conservative treatment were the control group,then the effect of two groups after the treatment were compared.Results The symptomatic improvement rate of control group was 31.0%,cure rate was 51.7%,one case occurred rupture and bleeding,then it was turned to surgery,the incidence of complications was 3.4%,the symptomatic improvement rate of observation group was 100.0%,cure rate was 100.0%,two cases occurred complications such as infection and pleural effusion,and they were all cured with medicine,the incidence of complications was 8.0%,there were significant differences between the two groups（P0.05）.Conclusion The focal nodular hyperplasia of the liver is mainly diagnosed by pathological examination during or after the surgery,the first choice for the patients with obvious symptom and bigger lesions is surgical operation.