摘要
目的探讨慢性心力衰竭患者D-二聚体浓度的变化及与心功能之间的相互关系。方法检测所有入选对象的生化、D-二聚体浓度等指标。结果 D-二聚体浓度升高的发生率为36.7%,在心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ级患者中其发生率分别为0(0/10)、28.4%(71/250)、35.7%(50/140)、65.6%(59/90),P<0.05;心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ级的患者D-二聚体浓度中位数分别为146.0、239.0、314.5、670.0mg/L,P<0.05;心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ级的非房颤及非瓣膜性心脏病患者D-二聚体浓度中位数分别为146、232、356、650mg/L,进行多重比较,P<0.05。结论随着心功能分级增加,D-二聚体浓度逐渐增加。
Objective To explore the prevalence of D-dimer in inpatients with chronic heart failure （CHF） and assess the relationship among heart function. Methods The patients to be selected were measured laboratory measurements, D-dimer and so on. Results The prevalence of D-dimer could be shown 36.7% in all of the inpatients with CHF; The prevalence of D-dimer of the patients with CHF in NYHA Ⅰ,Ⅱ,Ⅲ,Ⅳ class was revealed 0 （0/10）, 28.4%（71/250）, 35.7%（50/140）, 65.6%（59/90）, P 〈 0.05. The median of D-dimer of all patients with CHF in NYHA Ⅰ,Ⅱ,Ⅲ,Ⅳ class was shown 146.0, 239.0, 314.5, 670.0 mg/L,P 〈 0.05; The median of D-dimer of all patients with non-atrial fibrillations with CHF in NY- HA Ⅰ,Ⅱ,Ⅲ,Ⅳ class was extended 146, 232, 356, 650 mg/L, P 〈 0.05. Conclusion High D-dimer are common finding in patients hospitalized with CHF, the degree of high D-dimer is correlated with the severity of CHF.
出处
《中国当代医药》
2012年第31期27-28,共2页
China Modern Medicine
基金
首都医学发展科研基金项目(2007-3184)
