益气养阴法治疗结肠黑变病的临床观察

Clinical observation of supplementing qi and nourishing yin in treatment of melanosis coli

目的探讨益气养阴法治疗结肠黑变病的临床疗效。方法选取本院2009年10月～2011年12月收治的结肠黑变病患者26例,随机分为两组,采用聚乙二醇散剂(冲水口服10g/次,2次/d,疗程4周)治疗的13例患者为对照组,采用益气养阴汤剂(水煎口服,1剂/d,分2次服用,疗程4周)治疗的13例患者为观察组,比较两组患者疗程结束后的症状疗效和肠镜改善情况。结果疗程结束后,观察组临床症状疗效总有效率(100.0%)明显高于对照组(69.2%),观察组结肠镜下临床疗效总有效率(100.0%)也明显高于对照组(61.5%),差异均有统计学意义(P<0.05)。结论益气养阴法治疗结肠黑变病临床疗效确切,可以有效促进肠动力并明显改善患者的临床症状,值得临床推广使用。

Objective To investigate the clinical curative effect of supplementing qi and nourishing yin in treatment of melanosis coli. Methods Twenty six patients with melanosis coli in our hospital from October 2009 to December 2011 were selected and divided into two groups randomly, thirteen patients used macrogol powder （flushing oral, 10 g/time, 2 times /d, course of 4 weeks） in treatment as control group, thirteen patients used supplementing qi and nourishing yin decoction （decoction oral, 1 agent/d, 2 times/d, course of 4 weeks） in the treatment as observation group. Improvement of symptom and colonoscopy were compared between two groups after the treatment. Results After treatment, the clinical total effective rate in observation group （100%） was significantly higher than that of control group （69.2%）. The total efficiency of clinical curative effect under colonoscopy in observation group （100%） was significantly higher than that in control group （61.5%）. The difference was statistically significant （P 0.05）. Conclusion Supplementing qi and nourishing yin in treatment of melanosis coli has clinical curative effect, which can promote intestinal motility and significantly improve the patient＇s clinical symptoms. It is worth for clinical use.