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脑源性神经生长因子与听觉中枢可塑性 被引量：2

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摘要 脑源性神经生长因子（brain—derived neurotrophic factor，BDNF）是神经营养蛋白家族中一重要成员，它通过“活性依赖”机制对听觉中枢神经元的可塑性变化进行调节，并受中枢听觉系统神经元活性的影响。本文综述了近年来对听觉中枢可塑性变化的研究及BDNF与听觉中枢可塑的相关性及可能的调节机制。
作者 王玉杏 徐鸥 黄河银 刘砚星 路虹
机构地区 河北医科大学第二医院耳鼻咽喉科 河北医科大学药理学教研室
出处 《国际耳鼻咽喉头颈外科杂志》 2012年第6期311-314,共4页 International Journal of Otolaryngology-Head and Neck Surgery
基金 河北省自然科学基金（C2011206036）和河北省卫生厅医学科学研究重点课题计划（20110375）联合资助
关键词 脑源性神经生长因子(Brain—Derived NEUROTROPHIC Factor) 听觉(Auditory Perception) 神经元可塑性(Neuronal Plasticity)
分类号 R285.5 [医药卫生—中药学]
  • 相关文献

参考文献23

  • 1Kappel V,Moreno AC, Buss CH. Plasticity of the auditorysystem : theoretical considerations. Braz J Otorhinolaryngol,2011, 77 (5) : 670-674.
  • 2Sharma A, Nash AA, Dorman M. Cortical development,plasticity and re-organization in children with cochlear implants. JCommun Disord, 2009,42 (4) : 272-279.
  • 3Hildebrandt H, Hoffmann NA, Illing RB. Synapticreorganization in the adult rat's ventral cochlear nucleus followingits total sensory deafferentation. PLoS One, 2011, 6 (8):e23686.
  • 4张萌,陈晓巍,田永胜.耳蜗毁损后小鼠听觉中枢的退行性改变[J].中华耳鼻咽喉头颈外科杂志,2009,44(7):571-576. 被引量：6
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二级参考文献11

  • 1Willott JF,Bross LS.Morphology of the octopus cell area of the cochlear nucleus in young and aging C57BL/6J and CBA/J mice.J Comp Neurol,1990,300:61-81.
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共引文献5

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二级引证文献7

国际耳鼻咽喉头颈外科杂志
2012年 第6期

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