周围神经中许旺细胞特异性标记物

Special Marker of Schwann Cell in Peripheral Nerve

周围神经损伤后,其近、远端神经纤维将发生瓦勒氏变性(Wallerian degeneration)。许旺细胞(Schwann Cell)起源于神经嵴细胞,是周围神经的种子细胞。目前周围神经损伤的修复,主要围绕神经内部结构重建,促进神经纤维再生进行。通过特异性标记物标记、识别移植的许旺细胞,对神经移植效果的评价至关重要。本文就许旺细胞比较常见的特异性标记物进行综述,以期为许旺细胞在周围神经损伤及组织工程方面的应用提供帮助。

After injury of peripheral nerve, the fibrin both in proximal and distal end will develop Wallerian degeneration. Schwann cell comes from nerve prickle cell and is seed cell of peripheral nerve. The repair of injury of peripheral nerve mainly focus on reconstruction of inner construction of nerve and improve regeneration of nervous fibrin. The evaluation of effects on nerve transfer is more important to recognize transferred Sehwann cells by marking special marker. The more common special markers of Schwann cells were reviewed in this paper. Schawann cells transfer may lead to clinical application of peripheral nerve injury.