桐庐地区原发性高血压患者抗高血压药使用情况分析

Analysis of the Use of Anti-hypertensive Drug with Primary Hypertension in Tonglu County

目的了解桐庐地区原发性高血压患者的药物治疗状况。方法采用自制的《原发性高血压患者用药情况调查表》,对2 091例患者进行问卷调查,并进行12个月随访。结果农村和城镇高血压患者的抗高血压药物选择存在用药差别。所有患者单一用药比例为83.45%,农村和城镇患者的单一用药比例分别为89.64%和75.62%,2者差异具有统计学意义(P<0.05)。农村和城镇患者的用药不依从分别为24.14%和18.74%,2者差异具有统计学意义(P<0.05)。所有患者用药不合理占21.76%,血压达标率为50.31%;通过用药干预不合理率下降为7.13%,血压达标率为63.46%。血压达标率因患者参保医疗保险险种、用药依从性、用药合理性等因素不同而不同,差异均具有统计学意义(P<0.05)。单一用药和联合用药的患者之间血压达标率差异无统计学意义(P>0.05)。结论对高血压患者要进一步强调用药的合理性和用药依从性,以进一步提高血压达标率,减少并发症的发生。

OBJECTIVE To introduce the current status of drug treatment of primary hypertension patients in Tonglu. METHODS With ＂Questionnaire of Drug Intake by Primary Hypertension Patients＂ as a tool, an investigation was conducted in 2 091 patients and the patients were recalled after 12 months. RESULTS There were differences between rural and urban hypertension patients in the selection of anti-hypertetlsive drugs. The number of patients receiving single-agent drug therapy accounted for 83.45% and there was a significant difference（P〈0.05） between rural and urban patients, which was 89.64% and 75.62%, respectively. The amount of rural and urban patients with medication non-compliance accounted for 24.14% and 18.74%, respectively, with a great difference between them. The use of unreasonable amount of prescriptions was accounting for 21.76% while compliance rate of blood pressure 50.31%. However, the unreasonable rate decreased to 7.13% while compliance rate of blood pressure increased to 63.46% through drug intervention. There was a significant difference （P〈0.05） in patients receiving medical insurances, medication compliance, reasonable medication and compliance rate of blood pressure. CONCLUSION It is important for hypertension patients to emphasize the necessity for medication reasonableness and medication compliance, which in order to improve the compliance rate of blood pressure and reduce the occurrence of complications.