有氧运动对阻塞性睡眠呼吸暂停低通气综合征患者心肺功能的影响

The impact of aerobic exercise on cardiorespiratory function in patients with obstructive sleep apnea/hypopnea syndrome

目的研究有氧运动对阻塞性睡眠呼吸暂停低通气综合征患者心肺功能的影响。方法选取阻塞性睡眠呼吸暂停低通气综合征患者84例，将上述患者按随机数字表法分为有氧运动组和对照组，每组42例。对照组给予日常生活活动能力训练，未给予其它运动训练；有氧运动组在日常生活活动能力训练的基础上参照美国心脏病学会制订的三阶段康复运动方案以及运动处方进行训练，每次运动时间30～45min，每周训练4。5次。2组患者均于治疗前和训练16周后（治疗后）接受活动平板实验、6rain步行试验和生活质量（QOL）评定。结果治疗前2组患者各项指标组间比较，差异均无统计学意义（P〉0．05）；治疗后有氧运动组患者最大氧耗量、CO，排出量、峰值心率、步行距离、每搏耗氧量均较治疗前明显提高，且改善幅度均优于对照组，差异均有统计学意义（P〈0．05）。结论有氧运动能显著改善阻塞性睡眠呼吸暂停低通气综合征心肺功能，提高患者生活质量（QOL）。

Objective To investigate the effects of aerobic exercise on cardiorespiratory function in patients with obstructive sleep apnea/hypopnea syndrome （ OSAHS）. Methods A total of 84 patients with OSAHS were randomly divided into a control group and an aerobic exercise group （42 in each group）. The control group was given only training in the activities of daily living （ADL）. The acrobic exercise group was given ADL training combined with aerobic exercise training. The regime was maintained for 16 weeks. Each patient＇s VOzmax, maximum heart rate （HRmax） , exercise time to exhaustion, 6-minute walking distance and quality of life （QOL） were evaluated before and after treatment. Results VOzmax, HRmax, VO2max/HRmax, maximum exercise time, 6-min walking dis- tance and QOL all increased significantly more in the aerobic exercise group compared with the control group. Conclusion Aerobic exercise training can significantly improve cardiorespiratory function in patients with OSAHS.