69例急性甲亢肌病临床特征分析及处理

Clinicial analysis of 69 patients with acute hyperthyroid myopathy and its treatment

对广西医科大学第一附属医院内分泌科1990年至2011年收治的急性甲亢肌病患者临床资料进行回顾性分析。纳入69例，临床症状以声音嘶哑最常见，17．4％的患者出现过呼吸困难，死亡原因包括呼吸肌麻痹和吸人性肺炎，急性甲亢肌病症状不典型，病情可迅速变化，应引起重视。主要给予抗甲亢药物、糖皮质激素、能量支持、对症等治疗，可取得良好的临床疗效。

Sixty-nine cases of acute hyperthyroid myopathy admitted from 1990 to 2011 were retrospectively analyzed. Hoarseness was the most common symptom; 17.39% of the patients had difficulty in breathing; respiratory muscle paralysis and aspiration pneumonia were the main causes of death. Efficient treatment lasting for two weeks was carried out in 81. 16% of the cases. Patients with severe bulbar palsy were often complicated with aspiration pneumonia and thus had high mortality rate. The main treatments in cluded anti-hyperthyroid drugs, corticosteroids, energy supports, and symptomatic management, which usually resulted in good clinical improvement.