期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

生命早期高脂暴露与代谢综合征 被引量：1

Relationship between exposure to high fat diet in early life and metabolic syndrome
下载PDF
导出
摘要 代谢综合征的发生可能源自于机体生命早期高脂暴露,进而在代谢等多方面产生程序化影响。该文对生命早期高脂暴露影响成年后胰岛素抵抗、脂代谢异常、高血压和肥胖等疾病发生的动物实验证据进行综述。 The exposure to high fat diet in early life may program metabolic and other systems, then causes metabolic syndrome. The animal experiment evidences about effects of high fat exposure in early life on adult insulin resistance, dyslipidemia, hypertension and adiposity are summarized in this paper.
作者 石文 杨科峰
机构地区 上海交通大学医学院营养系
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2012年第11期1521-1524,共4页 Journal of Shanghai Jiao tong University:Medical Science
基金 上海市教委科研创新项目(09YZ98)~~
关键词 高脂 生命早期 代谢综合征 high fat early life metabolic syndrome
分类号 R589.2 [医药卫生—内分泌]
  • 相关文献

参考文献21

  • 1Eckle RH,Grundy SM,Zimmer PZ. The metabolic syndrome[J].The Lancet,2005,(11):1415-1428.
  • 2Parente LB,Aguila MB,Mandarim-de-Lacerda CA. Deleterious effects of high-fat diet on perinatal and postweaning periods in adult rat offspring[J].Clinical Nutrition,2008,(04):1623-1634.
  • 3Howie GJ,Slobeda DM,Kamal T. Maternal nutritional history predicts obesity in adult offspring independent of postnatal diet[J].The Journal of Physiology,2009,(Pt4):905-915.
  • 4Dunn GA,Bale TL. Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice[J].Endocrinology,2009,(11):4999-5009.
  • 5Ashino NG,Saito KN,Souza FD. Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver[J].Journal of Nutritional Biochemistry,2012,(04):341-348.
  • 6McCurdy CE,Bishop JM,Williams SM. Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates[J].Journal of Clinical Investigation,2009,(02):323-335.
  • 7Grant WF,Gillingham MB,Batra AK. Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates[J].PLoS One,2011,(02):e17261.
  • 8Elahi MM,Cagampang FR,Mukhtar D. Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension,raised plasma lipids and fatty liver in mice[J].British Journal of Nutrition,2009,(04):514-519.
  • 9Jackson CM,Alexander BT,Roach L. Exposure to maternal overnutrition and a high fat diet during early postnatal development increases susceptibility to renal and metabolic injury later in life[J].Am J Physiol RenalPhysiol,2012,(06):F774-F783.
  • 10Rudyk O,Makra P,Jansen E. Increased cardiovascular reactivity to acute stress and salt-loading in adult male offspring of fat fed non-obese rats[J].PLoS One,2011,(10):e25250.

二级参考文献43

  • 1朱照平,黄宇烽,潘连军,徐华,夏欣一.营养性高脂血症对雄性新西兰兔睾丸和阴茎发育的影响[J].中华男科学杂志,2005,11(12):904-907. 被引量：11
  • 2BARKER D J P, OSMOND C. Infant mortality, childhood nutrition and ischaemic heart disease in England and Wales[ J]. Lancet, 1986, 327 : 1077-1081.
  • 3MONTOUDIS A, SIMONEAU L, LAFOND J. Influence of a maternal cholesterol-enriched diet on [ 1-14C ] -linoleic acid and L- [ 4, 5-3 H ] -leucine entry in plasma of rabbit offspring [ J ]. Life Sci, 2004, 74 : 1751-1762.
  • 4MARSEILLE-TREMBLAY C, GRAVEL A, LAFOND J, et al. Effect of an enriched cholesterol diet during gestation on fatty acid synthase, HMG-CoA reductase and SREBP-1/2 expressions in rabbits[ J]. Life Sci, 2007, 81:772-778.
  • 5SCHULPIS K H, GAVRILI S, VLACHOS G, et al. The effect of nutritional habits on maternal-neonatal lipid and lipoprutein serum levels in three different ethnic groups [ J ]. Ann Nutr Metab, 2006, 50:290-296.
  • 6KUNITOMO M. Oxidative stress and atherosclerosis [ J ]. Yakugaku Zasshi, 2007, 127 : 1997-2014.
  • 7SEPPO L, JAUHIAINEN T, NEVALA R, et al. Plant stanol esters in low-fat milk products lower serum total and LDL cholesterol[ J ]. Eur J Nutr, 2007, 46 (2) : 111-117.
  • 8SMITH D, ESPINO-MONTORO A, PEREZ-JIMENEZ F, et al. Effect of a high saturated fat and cholesterol diet supplemented with squalene or β-sitosterol on lipoprotein profile in fib hamsters [J]. Nutr Res, 2000, 20: 1309-1318.
  • 9BURKE K T, COLVIN P L, MYATT L, et al. Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster [ J ]. J Lipid Res, 2009, 50(6):1146-1155.
  • 10GOHARKHAY N, TAMAYO E H, YIN H, et al. Maternal hypercholesterolemia leads to activation of endogenous cholesterol synthesis in the offspring[ J]. Am J Obstet Gynecol, 2008, 199 (3) :273. e1-273, e6.

共引文献6

同被引文献7

引证文献1

二级引证文献2

上海交通大学学报（医学版）
2012年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部