手足口病住院患儿合并医院感染25例临床观察

Clinical observation of nosocomial infections in 25 children with hand, foot and mouth diseases

目的探讨儿科手足口病住院患儿合并医院感染的临床特征及相关因素。方法回顾性分析2009年1月-2011年10月512例手足口病住院患儿的临床资料。结果 512例住院患儿中有25例发生医院感染,感染率为4.88%;感染部位以下呼吸道为主占44.0%,其次为消化道占20.0%,再次为皮肤、上呼吸道和尿道,分别占16.0%、12.0%和8.0%;感染的病原菌主要是凝固酶阴性葡萄球菌和金黄色葡萄球菌,分别占81.0%和19.0%;引起医院感染的原因除与年龄、住院时间有关外,还与病区隔离不严、宣传力度不够、预防意识薄弱等有关。结论手足口病住院患儿合并医院感染发生率较高,应针对相关因素采取相应的预防措施,以降低医院感染的发生率。

OBJECTIVE To investigate the clinical characteristics and the related factors for nosocomial infections in hospitalized children with hand,foot and mouth disease.METHODS The clinical data of 512 hospitalized children with hand,foot and mouth diseases from Jan 2009 to Oct were retrospectively analyzed.RESULTS Of 512 hospitalized pediatric patients investigated,nosocomial infections occurred in 25 cases with the infection rate of 4.88%;the main infection site was respiratory tract（44.0%）,followed by gastrointestinal tract（20.0%）,skin（16.0%）,upper respiratory tract（12.0%）and urinary tract（%）;the main pathogens causing nosocomial infections were coagulase-negative Staphylococci and Staphylococcus aureus,accounting for 81.0% and 19.0%,respectively;in addition to the age and the hospital stay,the causes of nosocomial infections included the lax ward isolation,lack of publicity,and weak awareness of prevention as so on.CONCLUSION The incidence rate of nosocomial infections in the hospitalized children with hand,foot and mouth diseases is so high that it is necessary to take corresponding prevention measures according to the related factors so as to reduce nosocomial infections.